杰出校友(第六期) – Outstanding Alumni (Issue Six)

Issue Six (March 2013)

林义顺 Yishun Lin | 曾德富 Defu Zeng | 潘明桂 Minggui Pan

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林义顺

辛勤的园丁–记为创建和维护校友会网站平台而默默奉献的林义顺同学

转眼之间,我们福医旅美校友会伴随着新世纪的脚步走过了十三年的发展历程。十三年来,通过全体创会校友和历届工作团队的共同努力,秉持着服务校友、回馈母校的创会宗旨,校友会从无到有、从小到大,已成为北美福医校友的联系纽带及我们海外游子与母校之间的沟通桥梁,成为我们广大校友共同的精神家园。校友会网站作为我们旅美校友之间联谊交流的最重要平台,在校友会的工作中正发挥着无可替代的作用。

校友会网站的建立倾注了义顺同学的心血。早在1999年底我们筹备成立校友会期间,义顺同学就提出建立校友会网站的建议,并自告奋勇地承担起架设网站的具体任务。当时,个人电脑还正处于普及的阶段,我们大部分同学对于个人电脑的使用技能还在学习摸索中,网站还属于“新生事物”,对于架设网站的具体计划并没有多少慨念。没想到,经过几个星期的努力,他居然能利用平时所自学到的网络语言及相关知识成功地把校友会的网站给建立起来了。在校友会正式成立之时,这个网站开始同步运作,将校友会的信息及时在网站上刊登,并连续报导了当时校友会成立大会的盛况和一系列照片。作为这个网站的第一批“访客”之一,我深为这位“业余”网站建设者的专业技能和为校友会热心奉献的精神所折服。

网站的生命力在于网页版面和内容的不断丰富和更新,我们校友会网站之所以具有如此强大的吸引力,在于其内容的可读性、知识性、实用性、及时性、和多样性。为了实现这一目标,义顺同学在繁忙的工作之余花费了大量时间和精力致力于校友会网站的维护和内容更新,积极主动地查找资料,丰富网站内容,并多次将网站升级更新。近两年来,在他和林基祯等同学的努力下,校友会网站开设了校友博客(Blog)平台,极大地方便了校友之间的交流和沟通,为校友会工作增添了新的活力和凝聚力。这个网站作为我们旅美校友的精神乐园已成为我们日常生活中不可缺少的一部分,这其中,义顺同学付出了大量的时间和艰苦的努力。他就像一个园丁,在这个百花园里长期耕耘着、呵护着、浇灌着,任劳任怨,鞠躬尽瘁。

义顺同学对校友会的贡献远不止于校友会网站的服务方面。作为校友会的主要创建成员之一,他参与了校友会的筹备工作并担任首届秘书长。此后,又长期担任副会长职务为校友会的会务运作和发展尽心尽责。多年来他还兼任教育基金会共同主任,在评选奖学金的所有工作上一丝不苟。他谦和敦厚的个人特质、务实平稳的工作作风、丰富的社团工作经验及卓有远见的办会理念,深获历届会长的倚重和广大校友的信赖。正是有一批像他这样的热心校友十几年如一日地为校友会辛勤奉献,保证了我们这个草根社团的持续而稳定的兴旺局面。

作为福医七八级老同学,我有幸与义顺同学结识已近三十五年。我们俩不仅同窗,还一起在建阳地区医院参加临床实习,共同度过了难忘的五年校园生涯。毕业之后,因相继出国曾一度失去联系,在十几年前筹建校友会的一次聚会中意外地在纽约相聚,使我们有机会重续前缘。自我们相识的三十五年间,我们所生活着的社会环境发生了巨大的变化,我们这一代六零后的思想观念或多或少地受时代和环境的影响而潜移默化。难得的是义顺同学仍一如既往地保持着一股浓浓的书卷气,理性、淡定、严谨、求知不倦。这种心理特质使他在临床医学研究领域如鱼得水,颇有建树。

作为中年人,我们在经过了多年的奔波劳碌之后,终于可以静下心来回首人生所走过的路,并思量着怎样才能让自己的人生过得更加精彩。能轰轰烈烈地成就一番事业,是人生的一场精彩演出;而作为一朵不知名的小花,丰富着春天的色彩,温暖着他人的心灵,同样也是一种精彩。就这个意义而言,义顺同学是我辈当之无愧的楷模!

福医七八级校友 郑灵
2013年3月10日 (稿)

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defu-zeng

曾德富 Defu Zeng M.D.

Dr. Defu Zeng is currently a full professor at The Beckman Research Institute, City of Hope National Medical Center, one of the leading research medical center in USA and in Los Angeles California. He is also vice president of the American Association of Fujian Medical University Alumni (AAFMUA)

Dr. Zeng’s research interests focus on transplantation immune tolerance, which have been well funded by several sources, including NIH grants. Specifically, he has been working on projects that explore the pathogenesis of graft-versus-host disease (GVHD) and has, to this effect, developed new mouse models of chronic GVHD that may shed light on its pathogenesis in humans. He is also developing a radiation-free GVHD preventative conditioning regimen for induction of mixed chimerism in the therapy of autoimmune diseases. Dr. Zeng’s studies have provided significant insight into transplant biology, promoting the application of allogeneic hematopoietic cell transplantation as a curative therapy not only for patients with hematological malignancies but also for patients with variety of refractory autoimmune diseases as well.

Dr. Zeng has authored more than 50 peer-reviewed publications in distinguished journals such as Science Translational Medicine, Journal of Experimental Medicine, Journal of Clinical Investigation, Proceedings of the National Academic of Sciences, Blood, Diabetes, and Journal of Immunology. He was also invited to give more than 30 conference lectures at eminent universities and research institutes in the U.S.A as well as in China. Dr. Zeng is now a standing member of NIH study section of Transplantation, Tolerance, and Tumor (TTT).

Dr. Zeng graduated from Fujian Medical University (FMU) in 1985. He received his postdoctoral training at Stanford University (1993 – 1997). He then joined Stanford’s faculty where he continued his research career. Dr. Zeng joined the faculty team at City of Hope National Medical Center in 2003 and is currently a full professor and member of the comprehensive cancer center at its Beckman Research Institute of City of Hope.

Dr. Zeng has actively participated in AAFMUA activities since 2000 and has acted as a liaison between City of Hope National Medical Center and FMU, specifically overseeing the training of young medical scientists and PhD candidates from FMU, and facilitating an exchange program between visiting scholars from FMU and COH. In addition, Dr. Zeng recommended several of his colleagues on the faculty of COH as guest professors of FMU, some of whom have trained and continue to train joint PhD students from FMU.

As alumni of FMU, we are extremely proud of Dr. Zeng’s outstanding academic achievements and appreciate all he has done for AAFMUA and FMU.

福医七七级校友 黄若青
2013年9月 (稿)

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Dr. Minggui Pan


潘明桂 Minggui Pan M.D., Ph.D. – A Distinguished Physician Scientist

Dr. Minggui Pan (潘明桂) received his medical degree in 1984 from The Fujian Medical University. He went on to become a Master of Medicine in Internal Medicine/Nephrology at the Peking Union Medical College Hospital/Chinese Academy of Medical Sciences. He came to the United States in 1989 to further pursue his studies and obtain a Ph.D. degree in Molecular and Cellular Biology at the Oregon Health Sciences University in Portland. He then completed a post-doctoral fellowship at the Department of Molecular Biology at Tularik, Inc. (now part of Amgen, Inc.) in South San Francisco. He then completed his residency in internal medicine at the University of California at San Francisco affiliated St. Mary’s Medical Center in San Francisco and medical oncology fellowship at the Stanford University School of Medicine. In 2002, he joined the Division of Hematology and Medical Oncology of Kaiser Permanente Medical Center at Santa Clara, California as an attending physician. Dr. Pan is board-certified in Internal Medicine and Medical Oncology by the American Board of Internal Medicine. He currently serves as the Chief of Hematology/Medical Oncology at Kaiser Permanente as a clinical assistant professor in Stanford University School of Medicine and as an attending staff oncologist at Veterans Healthcare System Hospital and Medical Center, Palo Alto, CA. He is also a guest professor at the Fujian Medical University.

Dr. Pan is an excellent physician scientist and an outstanding medical oncologist. He is always outstanding in whatever he pursues. He was a Fellow of the Cure for Lymphoma Foundation and the Lymphoma Research Foundation of America and has authored more than 30 scientific papers on oncology and other scientific areas. He has published many articles in high quality peer reviewed journals such as Developmental Cell, Nature Review Clinical Oncology, Journal of Immunology, and others.

Dr. Pan is the recipient of numerous honors and awards including the prestigious “Sidney R. Garfield Exceptional Contribution Award” in 2012, which recognizes physicians who have been instrumental in the development and dissemination of new ideas that have a significant impact on patients, colleagues and the broader community. Under Dr. Pan’s leadership, Kaiser Permanente Medical Center at Santa Clara has successfully built an outstanding cancer program that includes a multidisciplinary cancer care team, an American College of Surgeons accredited Comprehensive Breast Care Center, a highly-informative Comprehensive Cancer Care website, and a program to help survivors live healthy and productive lives after their cancer treatment. In 2013, he received Kaiser Permanente Asian Pacific Heritage Award in addition to the several awards for his cancer research including a Merit Award in 2002, and the Young Investigator Award in 2001 from the American Society of Clinical Oncology.

Dr. Pan has actively participated in community services and professional organizations. He is a member of American Society of Clinical Oncology, American Association for the Advancement of Sciences and American Association of Immunologists as well as the director of the Membership Committee of Chinese American Hematologist/Oncologist Network. He has been serving in the American Association of FMU alumni (AAFMUA) leadership team for many years and is currently the vice president of AAFMUA and the co-director of the AAFMUA Committee of Clinical Medicine. He collaborates with the Fujian Medial University affiliated teaching hospital to establish a remote web based tumor board to promote the academic exchange, research and oncology service in Fujian.

You can click here to view Dr. Pan’s webpage

Dr. Pan’s selected publications:

1. Tian, W., Ding, W, Kim, Xu, X., Pan, M., and Chen, S. (2013) Efficacy and Safety Profile of Combining Agents Against Epidermal Growth Factor Receptor or Vascular Endothelium Growth Factor Receptor with Gemcitabine-Based Chemotherapy in Patients with Advanced Pancreatic Cancer: A Meta-analysis. Pancreatology. In Press.

2. Tian, W., Ding, W., Kim, K., Zheng, L., Zhang, L., Li, X., Gu, G., Zhang, L., Pan, M., and Chen, S. (2013) Efficacy and Safety Profile of Combining Vandetanib with Chemotherapy in Patients with Advanced Non-small Cell Lung Cancer: A meta-analysis. PLOSOne. In Press.

3. Tripathi, P., Wang, Y., Coussens, M., Manda, K.R., Casey, A.M., Lin, C., Poyo, E., Pfeifer, J.D., Basappa, N., Bates, C.M, Ma, L., Zhang, H., Pan, M., Ding, L., and Chen, F. (2013) Oncogene, in Press.

4. Pan, M., Xiong, Y., and Chen, F. (2013) NFAT gene family in inflammation and cancer. Current Molecular Medicine. 13: 1-12.

5. Chen, S. and Pan, M. NFAT signaling and bone homeostasis. (2013) Journal of Hematology and Thromboembolic Diseases. e1: 101.

6. Xiong, Y., Li, W., Yang, J., Shang, S., Pan, M., and Chang, C.-P. (2013) Neural crest Brg1 is essential for the survival and migration of neural crest cells for cardiovascular development. Proc. Natl. Aca. Sci. U.S.A. 110(5): 1738-43.

7. Xiong, Y., Li, W., Shang, C., Chen, R., Wu, B., Pan, M., Zhou, B., Longaker, M., and Chang, C.-P. (2013) Brg1 governs a tissue feedback mechanism to regulate stem cell activity during hair follicle regeneration. Developmental Cell. 25: 169-181.

8. Pan, M. (2011) Expression of calcium/calcineurin pathway regulated transcription factor NFATc1 and chromatin remodeling genes BRG1 and BRM in invasive breast cancer. European Journal of Cancer. 9: 18.

9. Pan, M. Winslow, M.M., Keum, J.S., and Crabtree, G.R. (2007) Stringent control of Nuclear NFATc1 Expression is critical for maintaining balanced immune response. Gene Therapy and Molecular Biology. 11: 171-176.

10. Pan, M. Santamaria, M., and Wollman, B. (2007) CNS response after erlotinib therapy in a patient with metastatic NSCLC with an EGFR mutation. Nature Reviews Clinical Oncology 4: 603-607.

11. Pan, M., Winslow, M. M., Chen, L., Kuo, A., Crabtree, G. R. (2007) Enhanced NFATc1 Nuclear Occupancy Causes T Cell Activation Independent of CD28 Costimulation. J Immunol. 2007. 178(7): 4315-4321.

12. Winslow, M., Pan, M, Starbuck, M., Gallo, E.M, Deng, L., Karsenty, G., and Crabtree, G.R. (2006) Calcineurin/NFAT Signaling in Osteoblasts Regulates Bone Mass. Developmental Cell 10: 771-782.

13. Vossler, M., Yao, H., York, R., Pan, M., Rim, C., and Stork, P.J.S. (1997) cAMP activates MAP kinase and Elk-1 through a B-Raf and Rap1-dependent pathway. Cell 89: 73-82.

14. Pan, M., Xiong, J., Copeland, N., Gilbert, D.J., Jenkins, N., and Goeddel, D.V. (1996) Sequence, genomic organization, and chromosomal localization of the mouse TRADD gene. J. Inflammation. 46: 168-175.

15. Hsu, H., Shu, H., Pan, M., and Goeddel, D.V. (1996) TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84, 299-308.

16. Pan, M., Wang, Y., Hirsch, D., Labudda, K., and Stork, P.J.S. (1995) The Wnt-1 proto-oncogene regulates MAP kinase activation by growth factors in PC12 cells. Oncogene 11: 2005-2010.

17. Rothe, M., Pan, M., Henzel, W., Ayeres, T., and Goeddel, D.V. (1995) The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 83: 1243-1252.

18. Pan, M., Rim, C., Lu, K., Florio, T., and Stork, P.J.S. (1993) Cloning and expression of two structurally distinct receptor-linked protein tyrosine phosphatase generated by RNA processing from a single gene. J. Biol. Chem. 267: 24169-24217.

19. Pan, M., Florio, T., and Stork, P.J.S. (1992) G protein activation of a hormone-stimulatd phosphatase in human tumor cells. Science 256: 1215-1217.

20. Florio, T., Pan, M., Hershberger, R.E., Civelli, O., and Stork, P.J.S. (1992) Dopaminergic inhibition of DNA synthesis in pituitary tumor cells is associated with phosphotyrosine phosphatse activity. J. Biol. Chem. 267: 24169-247172.

2014年2月 (稿)

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